As a CRPS attorney in San Diego, I keep on top of news and research that may benefit my clients with Chronic Regional Pain Syndrome as well as any cases related to CRPS. The following information about a possible new pain contributor in CRPS patients caught my attention this week. A study on mice conducted by John Hopkins University and the University of Maryland has found that a chemical released by the brain known to produce a feeling of happiness and a sense of well-being can actually be a contributor to Chronic Regional Pain Syndrome. Serotonin was found to provoke hyperactivity of TRPV1, the protein required to activate pain-sensing nerve cells.